It is common for women to have “mastalgia” (sore or tender breasts) the week before their period. The symptoms may be caused by a rise in the hormones, estrogen and progesterone. Breast discomfort can continue during menstruation; however, it is usually relieved when your period starts. Other possible causes of breast pain can be: a side effect of certain medicines such as starting birth control pills, breast cyst(s), a breast infection, a breast injury, long distance running, a poorly fitted bra, or pregnancy. Since your pain seems to be in a specific area of your breast(s), it’s a good idea to check in with your primary care provider (PCP). Tell your PCP if anyone in your family has had breast problems and if you could possibly be pregnant.